Effects of Somatostatin Analogs and Dopamine Agonists on Insulin-Like Growth Factor 2-Induced Insulin Receptor Isoform A Activation by Gastroenteropancreatic Neuroendocrine Tumor Cells
Author(s) -
Roxanne C.S. van Adrichem,
Wouter W. de Herder,
Kimberly Kamp,
Michael P. Brugts,
Ronald R. de Krijger,
Diana Sprij-Mooij,
Steven W. J. Lamberts,
Peter M. van Koetsveld,
J. A. M. J. L. Janssen,
Leo J. Hofland
Publication year - 2016
Publication title -
neuroendocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.493
H-Index - 101
eISSN - 1423-0194
pISSN - 0028-3835
DOI - 10.1159/000444280
Subject(s) - somatostatin , endocrinology , medicine , biology , insulin like growth factor , somatostatin receptor , receptor , growth factor , dopamine
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) express insulin-like growth factor (IGF)-related factors [IGF1, IGF2; insulin receptor (IR)-A, IR-B; IGF-binding protein (IGFBP) 1-3] as well as somatostatin (SSTRs) and dopamine D2 receptors (D2Rs).
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