Fractionation of Source Materials Leads to a High Reproducibility of the SQ House Dust Mite SLIT-Tablets | Zendy

Helene Henmar | Zendy; Sofie Marie Toft Frisenette | Zendy; Karin Grosch | Zendy; Kim G. Nielsen | Zendy; Gary A. Smith | Zendy; Susanne Sønderkær | Zendy; Jørgen Nedergaard Larsen | Zendy

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Fractionation of Source Materials Leads to a High Reproducibility of the SQ House Dust Mite SLIT-Tablets

Author(s) -

Helene Henmar,

Sofie Marie Toft Frisenette,

Karin Grosch,

Kim G. Nielsen,

Gary A. Smith,

Susanne Sønderkær,

Jørgen Nedergaard Larsen

Publication year - 2016

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000444016

Subject(s) - allergen , radial immunodiffusion , house dust mite , potency , chemistry , pyroglyphidae , mite , immunology , immunoglobulin e , allergy , reproducibility , medicine , chromatography , antibody , biology , biochemistry , in vitro , botany

The production of house dust mite (HDM) allergen products for allergy immunotherapy has traditionally been based on purified mite bodies or whole-mite culture, which are quite different source materials with a limited possibility for adjusting the chemical composition. The SQ HDM SLIT-tablet is a fast-dissolving pharmaceutical formulation that has been developed for sublingual immunotherapy (SLIT) of HDM respiratory allergic disease.

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