Effects of Obesity on Perivascular Adipose Tissue Vasorelaxant Function: Nitric Oxide, Inflammation and Elevated Systemic Blood Pressure | Zendy

Reza Aghamohammadzadeh | Zendy; Richard D. Unwin | Zendy; Adam Greenstein | Zendy; Anthony M. Heagerty | Zendy

Open Access

Effects of Obesity on Perivascular Adipose Tissue Vasorelaxant Function: Nitric Oxide, Inflammation and Elevated Systemic Blood Pressure

Author(s) -

Reza Aghamohammadzadeh,

Richard D. Unwin,

Adam Greenstein,

Anthony M. Heagerty

Publication year - 2015

Publication title -

journal of vascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.58

H-Index - 74

eISSN - 1423-0135

pISSN - 1018-1172

DOI - 10.1159/000443885

Subject(s) - endocrinology , medicine , adipose tissue , endothelium , nitric oxide , electrical impedance myography , chemistry , vasodilation , blood vessel , mesenteric arteries , contractility , leptin , sodium nitroprusside , obesity , artery

Perivascular adipose tissue (PVAT) surrounds most vessels in the human body. Healthy PVAT has a vasorelaxant effect which is not observed in obesity. We assessed the contribution of nitric oxide (NO), inflammation and endothelium to obesity-induced PVAT damage.

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