Association of FEF25-75% Impairment with Bronchial Hyperresponsiveness and Airway Inflammation in Subjects with Asthma-Like Symptoms
Author(s) -
Mario Malerba,
Alessandro Radaeli,
Alessia Olivini,
Giovanni Damiani,
Beatrice Ragnoli,
Valentina Sorbello,
Fabio Luigi Massimo Ricciardolo
Publication year - 2016
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000443797
Subject(s) - medicine , asthma , spirometry , exhaled nitric oxide , bronchial hyperresponsiveness , gastroenterology , methacholine , sputum , immunology , respiratory disease , lung , pathology , tuberculosis
Forced expiratory flow at 25 and 75% of the pulmonary volume (FEF25-75%) might be considered as a marker of early airway obstruction. FEF25-75% impairment might suggest earlier asthma recognition in symptomatic subjects even in the absence of other abnormal spirometry values.
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