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Cranial Magnetic Resonance Imaging in Elderly American Indians: Design, Methods, and Implementation of the Cerebrovascular Disease and Its Consequences in American Indians Study
Author(s) -
Astrid SuchyDicey,
Dean Shibata,
Lyle G. Best,
Steven P. Verney,
W.T. Longstreth,
Elisa T. Lee,
Peter M. Okin,
Richard Devereux,
Marcia O’Leary,
Tauqeer Ali,
Paul N. Jensen,
Clemma Muller,
Lonnie A. Nelson,
Everett R. Rhoades,
Tara Madhyastha,
Thomas J. Grabowski,
Norman J. Beauchamp,
Jason G. Umans,
Dedra Buchwald
Publication year - 2016
Publication title -
neuroepidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.217
H-Index - 87
eISSN - 1423-0208
pISSN - 0251-5350
DOI - 10.1159/000443277
Subject(s) - medicine , population , neurocognitive , cohort , demographics , medical history , disease , longitudinal study , gerontology , physical examination , cohort study , family medicine , surgery , demography , pathology , psychiatry , environmental health , cognition , sociology
The Cerebrovascular Disease and its Consequences in American Indians (CDCAI) Study recruited surviving members of a 20-year, longitudinal, population-based cohort of American Indians focused on cardiovascular disease, its risk factors, and its consequences. The goal of the CDCAI Study is to characterize the burden, risk factors, and manifestations of vascular brain injury identified on cranial MRI. The CDCAI Study investigators enrolled 1,033 participants aged 60 and older from 11 American Indian communities and tribes in the Northern Plains, Southern Plains, and Southwestern United States. In addition to cranial MRI performed according to standardized protocols, participants underwent extensive medical interview, clinical examination, neurocognitive testing, physical function evaluation, electrocardiogram, and provided blood and urine specimens. Participants also self-administered questionnaires covering demographics, quality of life, and medical history. This report describes the design, implementation, and some of the unique challenges of this study and data collection.

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