The Neurobiological Mechanisms of Gamma-Hydroxybutyrate Dependence and Withdrawal and Their Clinical Relevance: A Review | Zendy

Rama Kamal | Zendy; Martijn S. van Noorden | Zendy; Ernst Franzek | Zendy; Boukje A. G. Dijkstra | Zendy; A.J.M. Loonen | Zendy; Cornelius A.J. De Jong | Zendy

Open Access

The Neurobiological Mechanisms of Gamma-Hydroxybutyrate Dependence and Withdrawal and Their Clinical Relevance: A Review

Author(s) -

Rama Kamal,

Martijn S. van Noorden,

Ernst Franzek,

Boukje A. G. Dijkstra,

A.J.M. Loonen,

Cornelius A.J. De Jong

Publication year - 2016

Publication title -

neuropsychobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.71

H-Index - 83

eISSN - 1423-0224

pISSN - 0302-282X

DOI - 10.1159/000443173

Subject(s) - neuroscience , psychology , nucleus accumbens , pharmacology , medicine , dopamine

x03B3;-Hydroxybutyrate (GHB) has gained popularity as a drug of abuse. In the Netherlands the number of patients in treatment for GHB dependence has increased sharply. Clinical presentation of GHB withdrawal can be life threatening. We aim, through this overview, to explore the neurobiological pathways causing GHB dependency and withdrawal, and their implications for treatment choices.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research