Environmental Risk Factors and Amyotrophic Lateral Sclerosis: An Umbrella Review and Critical Assessment of Current Evidence from Systematic Reviews and Meta-Analyses of Observational Studies
Author(s) -
Lazaros Belbasis,
Vanesa Bellou,
Εvangelos Εvangelou
Publication year - 2016
Publication title -
neuroepidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.217
H-Index - 87
eISSN - 1423-0208
pISSN - 0251-5350
DOI - 10.1159/000443146
Subject(s) - medicine , amyotrophic lateral sclerosis , observational study , systematic review , meta analysis , intensive care medicine , physical medicine and rehabilitation , medline , disease , pathology , political science , law
The pathogenesis of amyotrophic lateral sclerosis (ALS) involves both environmental and genetic factors. Our study aimed at summarising the environmental risk factors for ALS, assessing the evidence for diverse biases, and pinpointing risk factors with high epidemiological credibility.
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