MicroRNA-124 Functions as a Tumor Suppressor by Regulating CDH2 and Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer | Zendy

Teng Ma | Zendy; Ye Zhao | Zendy; Ke Wei | Zendy; Guoliang Yao | Zendy; Chunfeng Pan | Zendy; Bin Liu | Zendy; Yang Xia | Zendy; Zhicheng He | Zendy; Xiaotong Qi | Zendy; Zhi Li | Zendy; Jun Wang | Zendy; Yongfeng Shao | Zendy

Open Access

MicroRNA-124 Functions as a Tumor Suppressor by Regulating CDH2 and Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer

Author(s) -

Teng Ma,

Ye Zhao,

Ke Wei,

Guoliang Yao,

Chunfeng Pan,

Bin Liu,

Yang Xia,

Zhicheng He,

Xiaotong Qi,

Zhi Li,

Jun Wang,

Yongfeng Shao

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000443097

Subject(s) - microrna , suppressor , epithelial–mesenchymal transition , mesenchymal stem cell , cancer research , cancer , biology , cell , transition (genetics) , microbiology and biotechnology , lung cancer , lung , medicine , pathology , metastasis , gene , genetics

Abnormal expression of microRNA-124 (miR-124) was found in non-small cell lung cancer (NSCLC). However, the association between miR-124 and CDH2 has not been reported yet. This study aims to reveal the inhibiting effects of miR-124 on the expression of CDH2 in NSCLC.

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