MicroRNA-125a-5p Contributes to Hepatic Stellate Cell Activation through Targeting FIH1 | Zendy

Guojun Li | Zendy; Jing Li | Zendy; Changshui Li | Zendy; Honggang Qi | Zendy; Peihong Dong | Zendy; Jianjian Zheng | Zendy; Fujun Yu | Zendy

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MicroRNA-125a-5p Contributes to Hepatic Stellate Cell Activation through Targeting FIH1

Author(s) -

Guojun Li,

Jing Li,

Changshui Li,

Honggang Qi,

Peihong Dong,

Jianjian Zheng,

Fujun Yu

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000443095

Subject(s) - hepatic stellate cell , microrna , hepatic fibrosis , cancer research , biology , cell growth , microbiology and biotechnology , apoptosis , fibrosis , medicine , gene , pathology , endocrinology , biochemistry

Emerging evidence shows that microRNAs (miRNAs) play a crucial role in the regulation of activation, proliferation and apoptosis of hepatic stellate cells (HSCs). Previous studies have indicated that miR-125a-5p is correlated with hepatitis B virus replication and disease progression. However, little is known about the biological role and underlying mechanism of miR-125a-5p in liver fibrosis.

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