The Tumor Suppressive Role of MiRNA-509-5p by Targeting FOXM1 in Non-Small Cell Lung Cancer
Author(s) -
Ning Ma,
Weihua Zhang,
Chenhui Qiao,
Hong Luo,
Xin Zhang,
Qiang Cai,
Suhua Zang,
Liang Zhang,
Jingyun Bai
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000443086
Subject(s) - foxm1 , microrna , viability assay , cancer research , vimentin , biology , cell growth , cell migration , lung cancer , luciferase , mtt assay , cell , cell culture , cell cycle , pathology , medicine , immunology , transfection , immunohistochemistry , gene , genetics
Deregulation of microRNAs (miRNAs) expression is a frequent event in cancer development and progression. Recent studies have implied that abnormal expression of miRNAs is frequently observed in non-small cell lung cancer (NSCLC). Here, we examined the levels and biological functions of miR-509-5p in NSCLC.
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