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Changes in the MicroRNA Profile of the Mandible of Ovariectomized Mice
Author(s) -
Lingyu Hao,
Jia Li,
Yawen Tian,
Junhua Wu
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000443074
Subject(s) - microrna , ovariectomized rat , wnt signaling pathway , mandible (arthropod mouthpart) , femur , dental alveolus , medicine , bone mineral , biology , messenger rna , endocrinology , signal transduction , osteoporosis , dentistry , estrogen , microbiology and biotechnology , gene , genetics , botany , genus , paleontology
In postmenopausal women, a decrease in bone mineral density (BMD) at the hip and spine is associated with an increased risk of tooth loss, possibly caused by the loss of the alveolar bone. The present study explored the effect of the ovariectomy (OVX) of mice on the miRNA expression profile of their bones.

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