IL-10 Induces T Cell Exhaustion During Transplantation of Virus Infected Hearts | Zendy

Asmae Gassa | Zendy; Fu Jian | Zendy; Halime Kalkavan | Zendy; Vikas Duhan | Zendy; Nadine Honke | Zendy; Namir Shaabani | Zendy; Sarah-Kim Friedrich | Zendy; Sebastian Dolff | Zendy; Thorsten Wahlers | Zendy; Andreas Kribben | Zendy; Cornelia Hardt | Zendy; Philipp A. Lang | Zendy; Oliver Witzke | Zendy; Karl S. Lang | Zendy

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IL-10 Induces T Cell Exhaustion During Transplantation of Virus Infected Hearts

Author(s) -

Asmae Gassa,

Fu Jian,

Halime Kalkavan,

Vikas Duhan,

Nadine Honke,

Namir Shaabani,

Sarah-Kim Friedrich,

Sebastian Dolff,

Thorsten Wahlers,

Andreas Kribben,

Cornelia Hardt,

Philipp A. Lang,

Oliver Witzke,

Karl S. Lang

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000443067

Subject(s) - lymphocytic choriomeningitis , immune system , virus , immunology , transplantation , cd8 , t cell , biology , immunopathology , viral load , cytotoxic t cell , virology , medicine , biochemistry , in vitro

Unexpected transmissions of viral pathogens during solid organ transplantation (SOT) can result in severe, life-threatening diseases in transplant recipients. Immune activation contributes to disease onset. However mechanisms balancing the immune response against transmitted viral infection through organ transplantation remain unknown. Methods &

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