Estrogen Accelerates Cutaneous Wound Healing by Promoting Proliferation of Epidermal Keratinocytes via Erk/Akt Signaling Pathway
Author(s) -
Tao Zhou,
Zicheng Yang,
Yajie Chen,
Yu Chen,
Zongwei Huang,
Bo You,
Yi-zhi Peng,
Jing Chen
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000443048
Subject(s) - hacat , protein kinase b , mapk/erk pathway , proliferating cell nuclear antigen , cell growth , keratinocyte , wound healing , downregulation and upregulation , chemistry , microbiology and biotechnology , cancer research , pi3k/akt/mtor pathway , biology , signal transduction , endocrinology , cell culture , immunology , biochemistry , genetics , gene
Previous studies have established that estrogen is capable of accelerating cutaneous wound healing through multiple mechanisms, one of which involves affecting keratinocytes biological properties, such as migration, proliferation, etc. This study aims to reveal the underlying molecular mechanisms of estrogen promoting epidermal keratinocytes proliferation. Method &
Accelerating Research
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