Influence of Omalizumab on Allergen-Specific IgE in Patients with Adult Asthma | Zendy

Hiroko Mizuma | Zendy; Akihiko Tanaka | Zendy; Yoshitaka Uchida | Zendy; Akiko Fujiwara | Zendy; Ryo Manabe | Zendy; Hitomi Furukawa | Zendy; Naota Kuwahara | Zendy; Y Fukuda | Zendy; Tomoyuki Kimura | Zendy; Megumi Jinno | Zendy; Shin Ohta | Zendy; Mayumi Yamamoto | Zendy; Satoshi Matsukara | Zendy; Mitsuru Adachi | Zendy; Hironori Sagara | Zendy

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Influence of Omalizumab on Allergen-Specific IgE in Patients with Adult Asthma

Author(s) -

Hiroko Mizuma,

Akihiko Tanaka,

Yoshitaka Uchida,

Akiko Fujiwara,

Ryo Manabe,

Hitomi Furukawa,

Naota Kuwahara,

Y Fukuda,

Tomoyuki Kimura,

Megumi Jinno,

Shin Ohta,

Mayumi Yamamoto,

Satoshi Matsukara,

Mitsuru Adachi,

Hironori Sagara

Publication year - 2015

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000442668

Subject(s) - omalizumab , immunoglobulin e , asthma , medicine , immunology , allergen , allergy , antibody , seroconversion

Omalizumab, an anti-immunoglobulin E (IgE) monoclonal antibody, inhibits the binding of circulating IgE to mast cells and basophils, resulting in fewer episodes of airway inflammation, asthma symptoms and exacerbations in patients with severe allergic asthma. Treatment of patients with asthma using omalizumab increases serum total IgE (tIgE) levels. However, little is known about the influence of omalizumab on allergen-specific IgE (sIgE).

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