Curcumin Protects against Monosodium Glutamate Neurotoxicity and Decreasing NMDA2B and mGluR5 Expression in Rat Hippocampus | Zendy

Rania M. Khalil | Zendy; Naglaa F. Khedr | Zendy

Open Access

Curcumin Protects against Monosodium Glutamate Neurotoxicity and Decreasing NMDA2B and mGluR5 Expression in Rat Hippocampus

Author(s) -

Rania M. Khalil,

Naglaa F. Khedr

Publication year - 2016

Publication title -

neurosignals

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.755

H-Index - 67

eISSN - 1424-8638

pISSN - 1424-862X

DOI - 10.1159/000442614

Subject(s) - neurotoxicity , curcumin , monosodium glutamate , neuroprotection , metabotropic glutamate receptor 5 , pharmacology , glutamate receptor , acetylcholinesterase , metabotropic glutamate receptor , hippocampus , aché , medicine , chemistry , toxicity , endocrinology , receptor , biochemistry , enzyme

Monosodium glutamate (MSG) is a flavor enhancer used in food industries. MSG is well documented to induce neurotoxicity. Curcumin (CUR) reportedly possesses beneficial effects against various neurotoxic insults. Hence, this present study has been designed to evaluate the neuroprotective effect of curcumin on MSG-induced neurotoxicity in rats.

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