Evaluation of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry in Identification of Nontuberculous Mycobacteria | Zendy

Ivana Mareković | Zendy; Zrinka Bošnjak | Zendy; Marko Jakopović | Zendy; Zagorka Boras | Zendy; Mateja Janković | Zendy; Sanja PopovićGrle | Zendy

Open Access

Evaluation of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry in Identification of Nontuberculous Mycobacteria

Author(s) -

Ivana Mareković,

Zrinka Bošnjak,

Marko Jakopović,

Zagorka Boras,

Mateja Janković,

Sanja PopovićGrle

Publication year - 2016

Publication title -

chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.539

H-Index - 54

eISSN - 1421-9794

pISSN - 0009-3157

DOI - 10.1159/000442517

Subject(s) - mass spectrometry , nontuberculous mycobacteria , identification (biology) , chromatography , matrix assisted laser desorption/ionization , chemistry , analytical chemistry (journal) , medicine , mycobacterium , biology , desorption , pathology , tuberculosis , botany , organic chemistry , adsorption

Species-level identification of nontuberculous mycobacteria (NTM) is important in making decisions about the necessity and choice of antimicrobial treatment. The reason is predictable clinical significance and the susceptibility profile of specific NTM species. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is recognized as a diagnostic tool for routine identification of bacteria and yeasts in the clinical laboratory based on protein fingerprint analysis. The aim of the study was to evaluate MALDI-TOF MS in the identification of NTM.

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