Functional Genetic Variants of PPARγ and PPARα Encoding Peroxisome Proliferator-Activated Receptors and Susceptibility to Ischemic Stroke in Chinese Han Population | Zendy

Yeqing Tong | Zendy; Li Cai | Zendy; ShengHong Han | Zendy; Qing Lü | Zendy; Xuhua Guan | Zendy; Xiaoxv Ying | Zendy; Shuangyi Hou | Zendy; Fanxian Zhan | Zendy; Jinquan Cheng | Zendy; Jiafa Liu | Zendy

Open Access

Functional Genetic Variants of PPARγ and PPARα Encoding Peroxisome Proliferator-Activated Receptors and Susceptibility to Ischemic Stroke in Chinese Han Population

Author(s) -

Yeqing Tong,

Li Cai,

ShengHong Han,

Qing Lü,

Xuhua Guan,

Xiaoxv Ying,

Shuangyi Hou,

Fanxian Zhan,

Jinquan Cheng,

Jiafa Liu

Publication year - 2015

Publication title -

cerebrovascular diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.221

H-Index - 104

eISSN - 1421-9786

pISSN - 1015-9770

DOI - 10.1159/000442306

Subject(s) - medicine , peroxisome proliferator activated receptor , receptor , logistic regression , population , genotype , transcription factor , allele , bioinformatics , endocrinology , genetics , biology , gene , environmental health

PPARx03B3; and PPARα belong to a receptor family of ligand-activated transcription factors involved in the regulation of inflammation, cellular glucose uptake, protection against atherosclerosis and endothelial cell function. Through these effects, they might be involved with the ischemic stroke (IS).

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