UGT1A1*28 Genotypes and Respiratory Disease in Very Preterm Infants: A Cohort Study | Zendy

Jesper Padkær Petersen | Zendy; Finn Ebbesen | Zendy; Mads V. Hollegaard | Zendy; Sofia Andersson | Zendy; David M. Hougaard | Zendy; Ole ThorlaciusUssing | Zendy; Tine Brink Henriksen | Zendy

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UGT1A1<b>*</b>28 Genotypes and Respiratory Disease in Very Preterm Infants: A Cohort Study

Author(s) -

Jesper Padkær Petersen,

Finn Ebbesen,

Mads V. Hollegaard,

Sofia Andersson,

David M. Hougaard,

Ole ThorlaciusUssing,

Tine Brink Henriksen

Publication year - 2015

Publication title -

neonatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.399

H-Index - 84

eISSN - 1661-7819

pISSN - 1661-7800

DOI - 10.1159/000442042

Subject(s) - medicine , bronchopulmonary dysplasia , odds ratio , cohort , genotype , hazard ratio , gestational age , pediatrics , gastroenterology , pregnancy , confidence interval , biology , genetics , gene

Respiratory disease in the very preterm infant is frequent and often severe. Bilirubin is both a potent neurotoxin and antioxidant, and may have a clinical impact on preterm respiratory disease. The Gilbert genotype, the UGT1A1*28 allele, is the major known genetic cause of variation in bilirubin.

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