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The Prevalence and Management of Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis in China
Author(s) -
Zhiying Li,
Tiantian Ma,
Min Chen,
MingHui Zhao
Publication year - 2015
Publication title -
kidney diseases
Language(s) - English
Resource type - Journals
eISSN - 2296-9381
pISSN - 2296-9357
DOI - 10.1159/000441912
Subject(s) - medicine , microscopic polyangiitis , granulomatosis with polyangiitis , proteinase 3 , immunology , vasculitis , anti neutrophil cytoplasmic antibody , myeloperoxidase , population , eosinophilic , autoantibody , antibody , disease , pathology , inflammation , environmental health
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) comprises microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA) and eosinophilic GPA (EGPA). Myeloperoxidase (MPO) and proteinase 3 (PR3) are the main antigens for ANCA. AAV is a common multisystem autoimmune disease and most of the studies on AAV have been conducted in Western countries. Nowadays in China many efforts are made to investigate this disease.

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