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In vitro Quality of Platelets with Low Plasma Carryover Treated with Ultraviolet C Light for Pathogen Inactivation
Author(s) -
Lacey Johnson,
Ryan A. Hyland,
Shereen Tan,
Frank Tolksdorf,
Chryslain Sumian,
Axel Seltsam,
Denese C. Marks
Publication year - 2015
Publication title -
transfusion medicine and hemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 39
eISSN - 1660-3818
pISSN - 1660-3796
DOI - 10.1159/000441830
Subject(s) - platelet , in vitro , pathogen , ultraviolet , platelet rich plasma , chemistry , microbiology and biotechnology , medicine , immunology , biology , biochemistry , materials science , optoelectronics
The THERAFLEX UV-Platelets system uses shortwave ultraviolet C light (UVC, 254 nm) to inactivate pathogens in platelet components. Plasma carryover influences pathogen inactivation and platelet quality following treatment. The plasma carryover in the standard platelets produced by our institution are below the intended specification (<30%).

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