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Gastric Cancer Screening by Combined Assay for Serum Anti-<b><i>Helicobacter pylori</i></b> IgG Antibody and Serum Pepsinogen Levels - The ABC Method
Author(s) -
Yasuharu Yamaguchi,
Yasuhiko Nagata,
Ryuuta Hiratsuka,
Yoshihiko Kawase,
Tatsurou Tominaga,
Shunji Takeuchi,
Shinya Sakagami,
Shusei Ishida
Publication year - 2016
Publication title -
digestion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.882
H-Index - 75
eISSN - 1421-9867
pISSN - 0012-2823
DOI - 10.1159/000441742
Subject(s) - cancer , medicine , helicobacter pylori , gastroenterology , cancer screening , stomach
Helicobacter pylori (Hp) infection and gastric atrophy are both risk factors for gastric cancer. Recently it has been found that X-ray examination for gastric cancer screening does not have much effect on the detection rate for gastric cancer in Japan. A candidate for a new mass screening for gastric cancer, the ABC method, using the combination assay of Hp and serum pepsinogen, was useful for identifying the development of gastric cancer in high-risk and low-risk populations. People with higher cancer risk are recommended to receive endoscopy. The ABC method was carried out as a gastric cancer mass-screening on the initiative of Nishitokyo Medical Association in Nishitokyo city from 2011. This paper reviewed the present status of gastric cancer screening using the ABC method, including the latest results of our ongoing screening.

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