Chromosomal Abnormalities in Embryonic and Somatic Stem Cells | Zendy

Paola Rebuzzini | Zendy; Maurizio Zuccotti | Zendy; Carlo Alberto Redi | Zendy; Silvia Garagna | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Chromosomal Abnormalities in Embryonic and Somatic Stem Cells

Author(s) -

Paola Rebuzzini,

Maurizio Zuccotti,

Carlo Alberto Redi,

Silvia Garagna

Publication year - 2015

Publication title -

cytogenetic and genome research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.571

H-Index - 88

ISSN - 1424-8581

DOI - 10.1159/000441645

Subject(s) - biology , embryonic stem cell , somatic cell , induced pluripotent stem cell , karyotype , regenerative medicine , stem cell , genetics , chromosome , microbiology and biotechnology , gene

The potential use of stem cells (SCs) for tissue engineering, regenerative medicine, disease modeling, toxicological studies, drug delivery, and as in vitro model for the study of basic developmental processes implies large-scale in vitro culture. Here, after a brief description of the main techniques used for karyotype analysis, we will give a detailed overview of the chromosome abnormalities described in pluripotent (embryonic and induced pluripotent SCs) and somatic SCs, and the possible causes of their origin during culture.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research