PET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy Bodies
Author(s) -
Stephen N. Gomperts,
Marta Marquié,
Joseph J. Locascio,
Steve Bayer,
Keith A. Johnson,
John H. Growdon
Publication year - 2015
Publication title -
neurodegenerative diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.98
H-Index - 57
eISSN - 1660-2862
pISSN - 1660-2854
DOI - 10.1159/000441421
Subject(s) - dementia with lewy bodies , pittsburgh compound b , dementia , parkinson's disease , medicine , cognitive decline , dopamine transporter , neuropsychology , putamen , psychology , lewy body , neuropathology , cognitive impairment , disease , pathology , neuroscience , cognition , dopamine , dopaminergic
Effective therapies for dementia with Lewy bodies (DLB) and Parkinson's disease (PD) dementia will require accurate diagnosis and an understanding of the contribution of distinct molecular pathologies to these diseases. We seek to use imaging biomarkers to improve diagnostic accuracy and to clarify the contribution of molecular species to cognitive impairment in DLB and PD.
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