Hepatorenal Acute Kidney Injury and the Importance of Raising Mean Arterial Pressure
Author(s) -
Juan Carlos Q. Velez,
Manish Kadian,
Margarita Taburyanskaya,
Nicole Bohm,
Tracie A. Delay,
Nithin Karakala,
Don C. Rockey,
Paul J. Nietert,
Andrew J. Goodwin,
Timothy P. Whelan
Publication year - 2015
Publication title -
the nephron journals/nephron journals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.951
H-Index - 72
eISSN - 2235-3186
pISSN - 1660-8151
DOI - 10.1159/000441151
Subject(s) - midodrine , medicine , mean arterial pressure , octreotide , quartile , creatinine , renal function , hepatorenal syndrome , blood pressure , acute kidney injury , urology , gastroenterology , cardiology , endocrinology , heart rate , somatostatin , cirrhosis , confidence interval , orthostatic vital signs
The efficacy of vasoconstrictors in hepatorenal syndrome (HRS) is variable. We hypothesized that the effectiveness of vasoconstrictor therapy in improving kidney function ultimately relates to the magnitude of the achieved mean arterial pressure (MAP) increase.
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