The Role of Congestion in Cardiorenal Syndrome Type 2: New Pathophysiological Insights into an Experimental Model of Heart Failure | Zendy

Annalisa Angelini | Zendy; Chiara Castellani | Zendy; Grazia Maria Virzì | Zendy; Marny Fedrigo | Zendy; Gaetano Thiene | Zendy; Marialuisa Valente | Zendy; Claudio Ronco | Zendy; Giorgio Vescovo | Zendy

Open Access

The Role of Congestion in Cardiorenal Syndrome Type 2: New Pathophysiological Insights into an Experimental Model of Heart Failure

Author(s) -

Annalisa Angelini,

Chiara Castellani,

Grazia Maria Virzì,

Marny Fedrigo,

Gaetano Thiene,

Marialuisa Valente,

Claudio Ronco,

Giorgio Vescovo

Publication year - 2015

Publication title -

cardiorenal medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.661

H-Index - 21

eISSN - 1664-3828

pISSN - 1664-5502

DOI - 10.1159/000440775

Subject(s) - cardiorenal syndrome , medicine , heart failure , natriuretic peptide , endocrinology , left ventricular hypertrophy , creatinine , proinflammatory cytokine , cardiology , inflammation , blood pressure

In cardiorenal syndrome type 2 (CRS2), the role of systemic congestion in heart failure (HF) is still obscure. We studied a model of CRS2 [monocrotaline (MCT)-treated rats] secondary to pulmonary hypertension and right ventricular (RV) failure in order to evaluate the contribution of prevalent congestion to the development of kidney injury.

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