Early Life Epidemiology of Alzheimer's Disease - A Critical Review | Zendy

Alon Seifan | Zendy; Matthew W. Schelke | Zendy; Yaa Obeng-Aduasare | Zendy; Richard Isaacson | Zendy

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Early Life Epidemiology of Alzheimer's Disease - A Critical Review

Author(s) -

Alon Seifan,

Matthew W. Schelke,

Yaa Obeng-Aduasare,

Richard Isaacson

Publication year - 2015

Publication title -

neuroepidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.217

H-Index - 87

eISSN - 1423-0208

pISSN - 0251-5350

DOI - 10.1159/000439568

Subject(s) - medicine , dementia , epidemiology , disease , life course approach , mechanism (biology) , socioeconomic status , alzheimer's disease , early childhood , cognition , vulnerability (computing) , neuroscience , psychiatry , developmental psychology , pathology , psychology , philosophy , population , environmental health , epistemology , computer security , computer science

As adult brain structure is primarily established in early life, genetic and environmental exposures in infancy and childhood influence the risk for Alzheimer disease (AD). In this systematic review, we identified several early life risk factors and discussed the evidence and underlying mechanism for each.

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