Apolipoprotein A-IV Inhibits AgRP/NPY Neurons and Activates Pro-Opiomelanocortin Neurons in the Arcuate Nucleus
Author(s) -
Chunling Yan,
Yanlin He,
Yuanzhong Xu,
Gang Shu,
Chunmei Wang,
Yongjie Yang,
Kenji Saito,
Pingwen Xu,
Antentor Hinton,
Xiaofeng Yan,
Likai Yu,
Qi Wu,
Patrick Tso,
Qingchun Tong,
Yong Xu
Publication year - 2015
Publication title -
neuroendocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.493
H-Index - 101
eISSN - 1423-0194
pISSN - 0028-3835
DOI - 10.1159/000439436
Subject(s) - medicine , endocrinology , neuropeptide y receptor , hypothalamus , arcuate nucleus , melanocortin , neuropeptide , receptor , chemistry , excitatory postsynaptic potential , biology , inhibitory postsynaptic potential
Apolipoprotein A-IV (apoA-IV) in the brain potently suppresses food intake. However, the mechanisms underlying its anorexigenic effects remain to be identified.
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