Comment on the Article by Torun et al. Entitled ‘Serum Paraoxonase 1 Activity and Oxidative Stress in Pediatric Patients with Pulmonary Tuberculosis'

activity in addition to the diseases which the authors stated [1] . The authors did not mention such contributing factors. In this regard, simple laboratory tests such as routine biochemistry tests, erythrocyte sedimentation rate and C-reactive protein could be carried out to exclude potential confounders. Also, dietary supplements such as vitamin C, vitamin E, iron, zinc and flavonoids can alter PON-1 activity [4] . Another contributing factor for PON-1 activity is the use of medicine: lipid-lowering drugs, aspirin, fenofibrate, dexamethasone and phenobarbital also affect PON-1 activity [5] . Although the study groups consisted of children, there could be different diseases related to the use of medicine. In conclusion, although this study contributed valuable information to the medical literature, clarifying these concerns could certainly provide a clearer picture when interpreting PON-1 activity among participants.