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Choice of Reference Serum Creatinine in Defining Acute Kidney Injury
Author(s) -
Edward D. Siew,
Michael E. Matheny
Publication year - 2015
Publication title -
˜the œnephron journals/nephron journals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.951
H-Index - 72
eISSN - 2235-3186
pISSN - 1660-8151
DOI - 10.1159/000439144
Subject(s) - medicine , creatinine , renal function , acute kidney injury , nephrology , incidence (geometry) , urology , intensive care medicine , optics , physics
The study of acute kidney injury (AKI) has expanded with the increasing availability of electronic health records and the use of standardized definitions. Understanding the impact of AKI between settings is limited by heterogeneity in the selection of reference creatinine to anchor the definition of AKI. In this mini-review, we discuss different approaches used to select reference creatinine and their relative merits and limitations.

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