Lupus Nephritis: A Different Disease in European Patients?
Author(s) -
Vladimı́r Tesař,
Zdenka Hrušková
Publication year - 2015
Publication title -
kidney diseases
Language(s) - English
Resource type - Journals
eISSN - 2296-9381
pISSN - 2296-9357
DOI - 10.1159/000438844
Subject(s) - medicine , lupus nephritis , rituximab , belimumab , cyclophosphamide , ethnic group , disease , systemic lupus erythematosus , immunology , gastroenterology , chemotherapy , lymphoma , b cell activating factor , b cell , antibody , sociology , anthropology
Lupus nephritis (LN) is still associated with significant mortality and substantial risk of progression to end-stage renal failure. Its outcome is related to the class and severity of LN and response to treatment, and it is poorer in patients with renal relapses. Ethnicity has a relatively well-defined impact on the outcome of the patients and their response to treatment and must always be taken into consideration in treatment decisions.
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