Circulating Insulin-Like Growth Factor-1 Level and Ovarian Cancer Risk
Author(s) -
Yiyang Li,
Yang Li,
Jialing Zhang,
Changjun Zheng,
He Zhu,
Huimei Yu,
Limei Fan
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000438652
Subject(s) - ovarian cancer , medicine , odds ratio , meta analysis , oncology , confidence interval , risk factor , cancer , case control study , insulin like growth factor , subgroup analysis , endocrinology , gynecology , growth factor , receptor
Insulin-like growth factor-1 (IGF-1) has an important role in cells' proliferation, differentiation and apoptosis, and it may be involved in carcinogenesis. Several epidemiological studies assessed the association between circulating IGF-1 level and ovarian cancer risk, but there was still no conclusive finding.
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