Insulin Stimulates Goose Liver Cell Growth by Activating PI3K-AKT-mTOR Signal Pathway | Zendy

Chunchun Han | Zendy; Shouhai Wei | Zendy; Qi Song | Zendy; Fang He | Zendy; Xiangping Xiong | Zendy; Huofu Wan | Zendy; Dandan Liu | Zendy; Fengjiang Ye | Zendy; Hehe Liu | Zendy; Liang Li | Zendy; Hongyong Xu | Zendy; Xiaohui Du | Zendy; Bo Kang | Zendy; Xianyin Zeng | Zendy

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Insulin Stimulates Goose Liver Cell Growth by Activating PI3K-AKT-mTOR Signal Pathway

Author(s) -

Chunchun Han,

Shouhai Wei,

Qi Song,

Fang He,

Xiangping Xiong,

Huofu Wan,

Dandan Liu,

Fengjiang Ye,

Hehe Liu,

Liang Li,

Hongyong Xu,

Xiaohui Du,

Bo Kang,

Xianyin Zeng

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000438650

Subject(s) - pi3k/akt/mtor pathway , protein kinase b , cell growth , insulin , biology , cell cycle , rptor , microbiology and biotechnology , signal transduction , apoptosis , chemistry , endocrinology , biochemistry

Recent studies have suggested a crucial role for PI3K-Akt-mTOR pathway in regulating cell proliferation, so we hypothesize that insulin acts goose hepatocellular growth by PI3K-Akt-mTOR signal pathway. Because the physiological status of liver cells in vitro is different from that in vivo, a simplified cell model in vitro was established.

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