Open AccessThe β3 Adrenergic Receptor Agonist BRL37344 Exacerbates Atrial Structural Remodeling Through iNOS Uncoupling in Canine Models of Atrial Fibrillation
Author(s) -
Xiaobing Wang,
Ruifeng Wang,
Guangzhong Liu,
Jingmei Dong,
Guanqi Zhao,
Jingpu Tian,
Jiayu Sun,
Xiu-Yue Jia,
Lin Wei,
Yuping Wang,
Weimin Li
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000438647
Subject(s) - medicine , nitric oxide synthase , endocrinology , tetrahydrobiopterin , agonist , enos , endothelial nos , atrial fibrillation , nitric oxide synthase type iii , nitric oxide , chemistry , receptor
The role of the β3-adrenergic receptor (β3-AR) agonist BRL37344 in atrial fibrillation (AF) structural remodeling and the underlying mechanisms as a therapeutic target were investigated.
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