Elevated Serum Concentration of Chitinase 3-Like 1 is an Independent Prognostic Biomarker for Poor Survival in Lung Cancer Patients | Zendy

Jiying Wang | Zendy; Zhaoying Sheng | Zendy; Wenyan Yang | Zendy; Yong Cai | Zendy

Open Access

Elevated Serum Concentration of Chitinase 3-Like 1 is an Independent Prognostic Biomarker for Poor Survival in Lung Cancer Patients

Author(s) -

Jiying Wang,

Zhaoying Sheng,

Wenyan Yang,

Yong Cai

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000438643

Subject(s) - lung cancer , medicine , hazard ratio , oncology , biomarker , confidence interval , cancer , meta analysis , proportional hazards model , survival analysis , subgroup analysis , biology , biochemistry

The chitinase 3-like 1 (CHI3L1) has an important role in cancer progression, and high CHI3L1 expression is associated with the development and progression of cancers. Previous studies had been controversial with respect to the association between CHI3L1 expression and lung cancer prognosis. Thus, we performed a meta-analysis to investigate the prognostic value of CHI3L1 expression in lung cancer.

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