Comparative Profiling of Triple-Negative Breast Carcinomas Tissue Glycoproteome by Sequential Purification of Glycoproteins and Stable Isotope Labeling
Author(s) -
Xiang Chen,
Jindao Wu,
Huaxing Huang,
Qiang Ding,
Xiaoan Liu,
Lin Chen,
Xiaoming Zha,
Mengdi Liang,
Jing He,
Qiannan Zhu,
Shui Wang,
Tiansong Xia
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000438613
Subject(s) - glycoprotein , triple negative breast cancer , agrin , cancer research , western blot , breast cancer , proteomics , biology , receptor , chemistry , medicine , microbiology and biotechnology , cancer , biochemistry , acetylcholine receptor , gene
Women with triple negative breast cancers (TNBCs) have a poor prognosis due to lack of suitable targeted therapies. Changes in the protein glycosylation are increasingly being recognized as an important modification associated with cancer etiology.
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