Open AccessAlleviation of Lipopolysaccharides-Induced Acute Lung Injury by MiR-454
Author(s) -
Zhengang Tao,
Ying Yuan,
Qingwu Liao
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000438609
Subject(s) - cxcl1 , lung , proinflammatory cytokine , microrna , pathogenesis , medicine , chemokine , flow cytometry , immunology , cancer research , cytokine , inflammation , biology , gene , biochemistry
Although acute lung injury (ALI) is an important and common disease in humans, its pathogenesis is poorly understood and its therapeutic outcome has not been significantly improved in the past years. Here, we examined whether application of microRNAs might inhibit the ALI-associated lung inflammatory, and subsequently reduce the injury.
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