Open AccessUp-Regulation of Voltage Gated K+ Channels Kv1.3 and Kv1.5 by Protein Kinase PKB/Akt
Author(s) -
Jamshed Warsi,
Myriam Fezai,
Mireia Fores,
Bernat Elvira,
Florian Läng
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000438598
Subject(s) - protein kinase b , microbiology and biotechnology , pi3k/akt/mtor pathway , chemistry , phosphorylation , biology , signal transduction
The voltage gated K+ channels Kv1.3 and Kv1.5 contribute to the orchestration of cell proliferation. Kinases participating in the regulation of cell proliferation include protein kinase B (PKB/Akt). The present study thus explored whether PKB/Akt modifies the abundance and function of Kv1.3 and Kv1.5.
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