The Expression of Markers Related to Ovarian Germline Stem Cells in the Mouse Ovarian Surface Epithelium and the Correlation with Notch Signaling Pathway | Zendy

Zezheng Pan | Zendy; Mengli Sun | Zendy; Jia Li | Zendy; Fangyue Zhou | Zendy; Xia Liang | Zendy; Jian Huang | Zendy; Tuochen Zheng | Zendy; Liping Zheng | Zendy; Yuehui Zheng | Zendy

Open Access

The Expression of Markers Related to Ovarian Germline Stem Cells in the Mouse Ovarian Surface Epithelium and the Correlation with Notch Signaling Pathway

Author(s) -

Zezheng Pan,

Mengli Sun,

Jia Li,

Fangyue Zhou,

Xia Liang,

Jian Huang,

Tuochen Zheng,

Liping Zheng,

Yuehui Zheng

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000438586

Subject(s) - notch signaling pathway , hes1 , stem cell , biology , germline , microbiology and biotechnology , hes3 signaling axis , stem cell marker , signal transduction , genetics , gene

Ovarian germline stem cells (OGSCs) have been shown to mainly exist in the ovarian surface epithelium (OSE), but the activity changes of germline stem cells during different reproductive stages and the potential regulatory signaling pathway are still unknown. The Notch signaling pathway plays a key role in cell development, primordial follicles and stem cell proliferation. However, whether it plays a role in the proliferation of OGSCs is unknown. Here, we analyzed the activity changes of germline stem cells and the correlation between germline stem cells and the Notch signaling pathway.

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