Decreased Osteopontin Expression as a Reliable Prognostic Indicator of Improvement in Pulmonary Tuberculosis: Impact of the Level of Interferon-γ-Inducible Protein 10
Author(s) -
Yunan Zhu,
Hongyu Jia,
Jianing Chen,
Guangying Cui,
Hainv Gao,
Yingfeng Wei,
Chong Lu,
Lin Wang,
Toshimitsu Uede,
Hongyan Diao
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000438559
Subject(s) - osteopontin , pulmonary tuberculosis , tuberculosis , medicine , interferon , interferon gamma , interferon γ , immunology , protein expression , cancer research , biology , pathology , cytokine , biochemistry , gene
Osteopontin (OPN) expression is increased during the course of various chronic inflammatory diseases, including tuberculosis (TB). However, its prognostic value in TB management remains unclear. This study aimed to determine whether OPN could associate with other cytokines serving as a reliable biomarker for evaluating the effectiveness of early anti-TB treatments.
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