Endothelin-1 Overexpression Improves Renal Function in eNOS Knockout Mice | Zendy

Oleg Tsuprykov | Zendy; Lyubov Chaykovska | Zendy; Axel Kretschmer | Zendy; JohannesPeter Stasch | Zendy; Thiemo Pfab | Zendy; Katharina Krause-Relle | Zendy; Christoph Reichetzeder | Zendy; Philipp Kalk | Zendy; Jerzy Adamski | Zendy; Berthold Hocher | Zendy

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Endothelin-1 Overexpression Improves Renal Function in eNOS Knockout Mice

Author(s) -

Oleg Tsuprykov,

Lyubov Chaykovska,

Axel Kretschmer,

JohannesPeter Stasch,

Thiemo Pfab,

Katharina Krause-Relle,

Christoph Reichetzeder,

Philipp Kalk,

Jerzy Adamski,

Berthold Hocher

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000438516

Subject(s) - enos , endocrinology , medicine , knockout mouse , renal function , kidney , chemistry , nitric oxide , biology , nitric oxide synthase , receptor

To investigate the renal phenotype under conditions of an activated renal ET-1 system in the status of nitric oxide deficiency, we compared kidney function and morphology in wild-type, ET-1 transgenic (ET+/+), endothelial nitric oxide synthase knockout (eNOS-/-) and ET+/+eNOS-/- mice.

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