Patients Tested at a Laboratory for Hereditary Cancer Syndromes Show an Overlap for Multiple Syndromes in Their Personal and Familial Cancer Histories | Zendy

Jennifer Saam | Zendy; Christopher Arnell | Zendy; Aaron Theisen | Zendy; Kelsey Moyes | Zendy; Ingrid Marino | Zendy; Kirstin M. Roundy | Zendy; Richard Wenstrup | Zendy

Open Access

Patients Tested at a Laboratory for Hereditary Cancer Syndromes Show an Overlap for Multiple Syndromes in Their Personal and Familial Cancer Histories

Author(s) -

Jennifer Saam,

Christopher Arnell,

Aaron Theisen,

Kelsey Moyes,

Ingrid Marino,

Kirstin M. Roundy,

Richard Wenstrup

Publication year - 2015

Publication title -

oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.987

H-Index - 98

eISSN - 1423-0232

pISSN - 0030-2414

DOI - 10.1159/000437307

Subject(s) - sanger sequencing , ion semiconductor sequencing , dna sequencing , personal genomics , computational biology , biology , multiplex , genetics , bioinformatics , medicine , gene , genomics , genome

Hereditary cancer testing guidelines are based on the premise that the common hereditary cancer syndromes have distinct, recognizable phenotypes. However, many syndromes present with overlapping cancers. The aim of this analysis was to identify the proportion of patients tested for Lynch syndrome (LS) or hereditary breast and ovarian cancer (HBOC) who met testing criteria for the other syndrome.

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