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The Effects of Thyroid Hormones on Gene Expression of Acyl-Coenzyme A Thioesterases in Adipose Tissue and Liver of Mice
Author(s) -
Kerstin Krause,
Juliane Weiner,
S Hönes,
Nora Klöting,
Eddy Rijntjes,
John T. Heiker,
Claudia Gebhardt,
Josef Köhrle,
Dagmar Führer,
Karen Geva Steinhoff,
Swen Hesse,
Lars C. Moeller,
Anke Tönjes
Publication year - 2015
Publication title -
european thyroid journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.23
H-Index - 10
eISSN - 2235-0802
pISSN - 2235-0640
DOI - 10.1159/000437304
Subject(s) - medicine , endocrinology , euthyroid , adipose tissue , white adipose tissue , thyroid , hormone , brown adipose tissue , fgf21 , gene expression , lipid metabolism , biology , gene , biochemistry , receptor , fibroblast growth factor
Thyroid hormones (TH) exert pleiotropic effects on glucose and lipid homeostasis. However, it is as yet unclear how TH regulate lipid storage and utilization in order to adapt to metabolic needs. Acyl-CoA thioesterases (ACOTs) have been proposed to play a regulatory role in the metabolism of fatty acids.

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