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Anti-PLA2R Antibodies as a Prognostic Factor in PLA2R-Related Membranous Nephropathy
Author(s) -
Sjoerd A.M.E.G. Timmermans,
Myrurgia Abdul Hamid,
Jan Willem Cohen Tervaert,
Jan Damoiseaux,
Pieter van Paassen
Publication year - 2015
Publication title -
american journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 85
eISSN - 1421-9670
pISSN - 0250-8095
DOI - 10.1159/000437236
Subject(s) - medicine , hazard ratio , gastroenterology , proteinuria , antibody , membranous nephropathy , cohort , immunology , kidney , confidence interval
The natural course of idiopathic membranous nephropathy (MN) varies, as it is known through favorable outcomes in most patients. However, one third of patients with idiopathic MN will slowly progress to end-stage renal disease (ESRD). To prevent disease progression, patients at high risk to develop ESRD are treated with immunosuppressive agents. Therefore, a correct selection of patients who need immunosuppressive treatment is important.

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