A Report of Stiff Person Syndrome in Tanzania with First Epidemiological Figures for Sub-Saharan Africa

upper normal reference 1.0). Four years later, she was diagnosed with breast carcinoma. Another patient presented with stiff limb syndrome, a partial or segmental onset variant following penetrating injury, which slowly generalized over several months. One patient had a subacute onset over a course of 2 weeks with mild encephalopathic features and saccadic eye movements, but noneIntroduction Stiff person syndrome (SPS) is a rare autoimmune movement disorder, with prevalence estimates ranging from 0.5 to 2 per 1,000,000 people [1, 2] . Its diagnosis is clinical, supported by the presence of anti-GAD or anti-amphiphysin antibodies. In this paper, we describe a series of SPS patients, estimate the prevalence in Tanzania and compare it with that of high income countries.