Buccal Cytome Biomarkers and Their Association with Plasma Folate, Vitamin B12 and Homocysteine in Alzheimer's Disease | Zendy

Philip Thomas | Zendy; Michael Fenech | Zendy

Open Access

Buccal Cytome Biomarkers and Their Association with Plasma Folate, Vitamin B<sub>12</sub> and Homocysteine in Alzheimer's Disease

Author(s) -

Philip Thomas,

Michael Fenech

Publication year - 2015

Publication title -

lifestyle genomics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.542

H-Index - 30

eISSN - 2504-3188

pISSN - 2504-3161

DOI - 10.1159/000435784

Subject(s) - medicine , endocrinology , micronucleus test , basal (medicine) , b vitamins , homocysteine , micronucleus , chemistry , microbiology and biotechnology , biology , toxicity , insulin

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder and is the commonest form of dementia. One aim of this study was to determine whether AD individuals have altered plasma folate, vitamin B12 and homocysteine (Hcy) levels compared to controls. The other aim was to investigate correlations between B vitamins and buccal biomarkers to test whether they are influenced by B vitamin status.

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