Open AccessComparison of Microneedles and Adhesive-Tape Stripping in Skin Preparation for Epicutaneous Allergen Delivery
Author(s) -
Lara Spina,
Michael Weisskopf,
Seraina von Moos,
Nicole Graf,
Thomas M. Kündig,
Gabriela Senti
Publication year - 2015
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000434681
Subject(s) - allergen , stratum corneum , dermis , allergy , medicine , immunology , skin patch , dermatology , pathology
Epicutaneous immunotherapy targets the network of dendritic cells in the epidermis. Allergen exposure of the dermal layers should be limited as these contain mast cells and blood vessels, which increases the risk for local and systemic allergic reactions.
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