Radiological and Pathological Predictors of Response to Neoadjuvant Chemotherapy in Breast Cancer: A Brief Literature Review | Zendy

Tejal Parekh | Zendy; David Dodwell | Zendy; Nisha Sharma | Zendy; Abeer M. Shaaban | Zendy

Open Access

Radiological and Pathological Predictors of Response to Neoadjuvant Chemotherapy in Breast Cancer: A Brief Literature Review

Author(s) -

Tejal Parekh,

David Dodwell,

Nisha Sharma,

Abeer M. Shaaban

Publication year - 2015

Publication title -

pathobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.941

H-Index - 53

eISSN - 1423-0291

pISSN - 1015-2008

DOI - 10.1159/000433582

Subject(s) - pathological , medicine , breast cancer , oncology , radiological weapon , chemotherapy , neoadjuvant therapy , cancer , bioinformatics , surgery , biology

Early clinical response to neoadjuvant chemotherapy (NACT) in breast cancer correlates with pathological response at surgery. A tailored approach using biomarkers to predict response to NACT has become a research priority. Predictors of response can be divided into pathological and radiological biomarkers. Advances in gene expression profiling and diffusion-weighted MRI techniques are used to predict tumour response, and combinations thereof are the future of predicting response to NACT in early-stage breast cancer.

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