Characterization of the Genotypic Profile of Hepatitis Delta Virus: Isolation of HDV Genotype-1 in the Western Amazon Region of Brazil | Zendy

Luan Felipo Botelho-Souza | Zendy; Deusilene Souza Vieira | Zendy; Alcione de Oliveira dos Santos | Zendy; André Vinycius Cunha Pereira | Zendy; Juan Miguel Villalobos-Salcedo | Zendy

Open Access

Characterization of the Genotypic Profile of Hepatitis Delta Virus: Isolation of HDV Genotype-1 in the Western Amazon Region of Brazil

Author(s) -

Luan Felipo Botelho-Souza,

Deusilene Souza Vieira,

Alcione de Oliveira dos Santos,

André Vinycius Cunha Pereira,

Juan Miguel Villalobos-Salcedo

Publication year - 2015

Publication title -

intervirology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.641

H-Index - 61

eISSN - 1423-0100

pISSN - 0300-5526

DOI - 10.1159/000431040

Subject(s) - genotype , virology , hepatitis d virus , fulminant hepatitis , hepatitis b virus , amazon rainforest , hepatitis d , population , biology , virus , medicine , hbsag , genetics , gene , ecology , environmental health

The hepatitis delta virus (HDV) is a hepatotropic subvirus that is dependent on the hepatitis B virus (HBV) and supplies the viral envelope containing the surface antigen of hepatitis B. Viral genetic diversity is related to the geographical origin of the isolates, and there are at least eight genotypes that are referred to as HDV-1 through HDV-8. HDV-3 is responsible for epidemics of severe and fulminant hepatitis, which are common in northeastern South America. HDV-3 is prevalent in the Brazilian Amazon and is associated with the increased aggressiveness of HDV infections. Although isolated, the characteristics of the clinical presentation of HDV-1 in the Amazon region have not yet been clearly reported.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research