Arrhythmogenic Remodeling in Murine Models of Deoxycorticosterone Acetate-Salt-Induced and 5/6-Subtotal Nephrectomy-Salt-Induced Cardiorenal Disease
Author(s) -
Magda S. C. Fontes,
Diana A. Papazova,
Arianne van Koppen,
Sanne de Jong,
Sanne M. Korte,
Lennart G. Bongartz,
Tri Q. Nguyen,
Marti F.A. Bierhuizen,
Teun P. de Boer,
Toon A.B. van Veen,
Marianne C. Verhaar,
Jaap A. Joles,
Harold V.M. van Rijen
Publication year - 2015
Publication title -
cardiorenal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.661
H-Index - 21
eISSN - 1664-3828
pISSN - 1664-5502
DOI - 10.1159/000430475
Subject(s) - medicine , cardiac fibrosis , endocrinology , heart failure , fibrosis , ventricle , kidney , nephrectomy
Renal failure is associated with adverse cardiac remodeling and sudden cardiac death. The mechanism leading to enhanced arrhythmogenicity in the cardiorenal syndrome is unclear. The aim of this study was to characterize electrophysiological and tissue alterations correlated with enhanced arrhythmogenicity in two distinct mouse models of renal failure.
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