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Long-Term Dietary Fructose Causes Gender-Different Metabolic and Vascular Dysfunction in Rats: Modulatory Effects of Resveratrol
Author(s) -
Mehmet Bilgehan Pektaş,
Gökhan Sadı,
Fatma Akar
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430405
Subject(s) - endocrinology , medicine , fructose , resveratrol , enos , insulin , metabolic syndrome , phenylephrine , sirtuin 1 , nitric oxide , nitric oxide synthase , biology , diabetes mellitus , downregulation and upregulation , blood pressure , biochemistry , gene
There is limited knowledge on the gender differences in the effects of dietary fructose. In the current study, we investigated whether long-term fructose intake impacts metabolic parameters and vascular reactivity differently between male and female rats. Moreover, we tested whether resveratrol has a gender-specific effectiveness on the alterations.

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